Doing radio was a special pleasure for the multivoiced Blanc. ``In radio, I could do 8 or 10 voices in a single program, and nobody would know who the hell I was. We had a studio audience of maybe 400 people.
In 1937, he joined the Warner Brothers animation unit which produced the Looney Tunes cartoons. He created voices for about 90 percent of Warner characters, including Bugs Bunny and Daffy Duck.
Among the many lines he repeatedly uttered that arguably rival those of Shakespeare in terms of familiarity, if not intellectual depth: "Eh . . . what's up, Doc?" through the lips of the wiseacre hare, Bugs Bunny; "I tawt I taw a putty tat ," from the tart-tongued canary Tweety, and "SSSSSsssuffering SSSSSuccotash," courtesy of Sylvester the sloppy cat.
Even as a youngster, he displayed his one-of-a-kind vocal gift, regaling his classmates and teachers with the piercing laugh he would later develop into Woody Woodpecker's signature call.
In the 1960's he also contributed to ''The Flintstones,'' the first animated situation comedy created for television and the first cartoon broadcast in prime time. For that series he supplied the voices for both Barney Rubble, the dull-witted neighbor of Fred and Wilma Flintstone, and Dino, the Flintstones' pet dinosaur.
Mr. Blanc's first major character was Porky Pig, the shy stammerer. The second was Happy Rabbit, which he saved from oblivion by providing a new name, Bugs, from the nickname of the character's illustrator, Ben Hardaway. Mr. Blanc then developed a distinctively brash voice for the character and came up with Bugs's catchy cue: ''What's up, doc?''
Bugs is the archetypal Warner Bros. character, a snarling, wise-talking urban rabbit who stands next to Disney's cute animal tykes as Humphrey Bogart does to Shirley Temple. Permanently chomping on a carrot and sneering "nyahh, what's up doc?" at hapless opponents, Bugs is, even more than Mickey Mouse, the great versatile creation of the cartoon short, at home in any historical period or geographical locale
Woody Woodpecker, devising the voice and laugh and then passing them on to a succession of others when an exclusive contract with Warners prevented him from continuing with Walter Lantz; the Tasmanian Devil, inarticulate but a furiously munching fiend, appetite incarnate; Speedy Gonzalez, the one-gag mouse with the perky Mexican accent; and Yosemite Sam, "the blood-thirstiest, shoot-'em firstiest, goshdarn worstiest bandit North, South, East and West of the Pecos!
In reviewing his career late in life, Blanc reflected that Yosemite Sam and Foghorn Leghorn were the characters hardest on his voice. He died in Los Angeles in 1989.
His tombstone reads, “That’s All Folks.”
The younger Blanc has carried on his father's tradition and recently recorded Bugs Bunny singing "Happy Birthday" greetings to more than 1,400 different names for a computerized 900 telephone service.